جزئیات محصول
محل منبع: چین
نام تجاری: Hongbaiyi
گواهی: COA, HPLC MR
شماره مدل: HBY-Livagen
سند: بروشور محصول PDF
شرایط پرداخت و حمل و نقل
مقدار حداقل تعداد سفارش: 5 کیت
قیمت: قابل مذاکره
جزئیات بسته بندی: 20 میلی گرم یا با توجه به نیاز مشتری.
زمان تحویل: 3-5 روز کاری پس از پرداخت شما
شرایط پرداخت: علی بابا، T/T، وسترن یونیون
قابلیت ارائه: 20000 جعبه در ماه
نام محصول: |
اپیتالون 20 میلی گرم |
شکل: |
تنظیم کننده زیستی تتراپپتیدی مصنوعی در ویال پودر لیوفیلیزه |
توالی اسید آمینه: |
Ala-Glu-Asp-Gly (AEDG) |
شماره CA: |
307297-39-8 |
فرمول: |
C14H22N4O3 |
وزن مولکولی: |
390.35 |
مکانیسم اولیه: |
آنزیم تلومراز را برای افزایش طول تلومرها فعال می کند و باعث افزایش طول عمر سلولی و کاهش زوال مرتبط ب |
توابع کلیدی تحقیق: |
ضد پیری (بازیابی بیان ژن جوان)؛ آنتی اکسیدان (گلوتاتیون را افزایش می دهد، اکسیداسیون لیپید را کاهش م |
خلوص: |
≥99٪ (دارای گواهینامه HPLC) |
نام محصول: |
اپیتالون 20 میلی گرم |
شکل: |
تنظیم کننده زیستی تتراپپتیدی مصنوعی در ویال پودر لیوفیلیزه |
توالی اسید آمینه: |
Ala-Glu-Asp-Gly (AEDG) |
شماره CA: |
307297-39-8 |
فرمول: |
C14H22N4O3 |
وزن مولکولی: |
390.35 |
مکانیسم اولیه: |
آنزیم تلومراز را برای افزایش طول تلومرها فعال می کند و باعث افزایش طول عمر سلولی و کاهش زوال مرتبط ب |
توابع کلیدی تحقیق: |
ضد پیری (بازیابی بیان ژن جوان)؛ آنتی اکسیدان (گلوتاتیون را افزایش می دهد، اکسیداسیون لیپید را کاهش م |
خلوص: |
≥99٪ (دارای گواهینامه HPLC) |
99%HPLC Epithalon 20mg Bioregulator Vial For Promoting Cellular Longevity
Epithalon (Epitalon; H-Ala-Glu-Asp-Gly-OH) is a synthetic tetrapeptide bioregulator from pineal extract epithalamin, sold as 20mg lyophilized vials (≥99% purity) for lab research only. Targets telomerase activation, telomere lengthening, epigenetics; not approved for human/veterinary use. Focus: anti-aging, oncology, immunology.
| Property | Details |
|---|---|
| Product Name | Epithalon (also Epitalon, Epithalone, Epithalamin) |
| Description | Sold as 20mg lyophilized powder vial for laboratory use only. |
| CAS Number | 307297-39-8 |
| Sequence | Ala-Glu-Asp-Gly (AEDG) |
| Molecular Formula | C₁₄H₂₂N₄O₉ |
| Molecular Weight | 390.35 g/mol (or 390.349 g/mol) |
| Color | White |
| Purity | ≥99% (HPLC-tested; USA-made available from suppliers like Peptide Sciences) |
| Form | Lyophilized powder (freeze-dried for stability) |
| Target | Cell Cycle/DNA Damage pathway |
| Availability | 20mg vial: |
5–10mg/day SC in rodents (10–20mg days, 1–2mg/year cycles); reconstitute in bacteriostatic water. No human scaling.
Storage & Handling
| Category | Details |
|---|---|
| Storage Conditions | Powder: -80°C (2 years); -20°C (1 year) - In solvent: -80°C (6 months); -20°C (1 month) - Sealed, away from moisture/light. |
| Solubility (In Vitro) | Water: ≥50 mg/mL (128.09 mM; saturation unknown) - Stock Solutions (examples): - 1 mg: 2.5618 mL H₂O - 5 mg: 12.8090 mL H₂O - 10 mg: 25.6180 mL H₂O - Reconstitute with bacteriostatic water for research protocols. |
| Handling Precautions | Sterile techniques required. For lab use only; avoid ingestion/injection in non-research settings. |
Biological Activity & Functions (Research Contexts)
Epithalon acts as an anti-aging agent by activating telomerase, elongating telomeres, and modulating gene expression. Key mechanisms include epigenetic regulation, free radical scavenging, and pineal gland support (e.g., melatonin synthesis). Dose-dependent; effects observed in cell cultures, rodents, insects, and limited primate models.
| Function Category | Detailed Research Functions |
|---|---|
| Anti-Aging & Longevity | Activates telomerase to elongate telomeres, reducing cellular senescence. - Prolongs lifespan: 52% in fruit flies/rats; 27% in tumor-prone mice. - Eliminates free radicals; restores youthful gene activity (e.g., CD5 for immune differentiation, IL-2 for WBC regulation, MMP2 for inflammation control). - Increases interferon gamma in aging lymphocytes for viral defense. |
| DNA & Gene Regulation | Interacts with DNA promoters to upregulate genes: Tram1 (protein production), Arylalkylamine-N-acetyltransferase (melatonin), pCREB (circadian/anti-cancer), telomerase (cell longevity). - Reduces DNA errors/mutations; prevents apoptosis via decreased caspase-3. |
| Immune & Reproductive Support | Delays age-related decline in reproductive/immune systems. - Boosts T-cell function; enhances interferon production against infections. |
| Skin & Tissue Repair | Activates fibroblasts (30–45% increase in rodents) for collagen/elastin synthesis. - Accelerates wound healing; offsets age-related skin degradation. |
| Oncology Research | Inhibits spontaneous tumor development/metastasis in mice/rats (e.g., Her-2/neu breast cancer, leukemia, testicular). - Activates PER1 protein to sensitize cancer cells to radiation; reduces secondary tumors. |
| Neurological & Endocrine | Restores melatonin/cortisol circadian rhythms in aging monkeys. - Influences AANAT/pCREB for melatonin secretion; neuroprotective effects. |
| Ocular Health | Prolongs retinal integrity; improves bioelectric function in 90% of retinitis pigmentosa rat models. - Potential for pigmental retinal degeneration studies. |
Product Images
FAQ
Q1: Can I get some samples?
A: Yes, we can provide samples. However, customers must bear the shipping cost.
Q2: How to pay?
A: We accept various payment methods, including T/T and other options.
Q 3: What is your MOQ (Minimum Order Quantity)?
A: Our standard MOQ is 5kits. However, smaller quantities, such as 100 grams, can be arranged for a corresponding sample fee.
Q 4: What is the shipping time?
A: Orders are usually shipped within 3-7 days with a tracking number. Delivery times vary by destination. Please get in touch with us for details.
